Give the Red Stuff.
Time and place for everything. Please give the red stuff, blood when needed. The only enemy is patient refusal and the obedience to religious practice like Jehovah Witnesses. Whole blood is better than component replacement. Deal with the resources you have.
Give it early to Trauma patients.
To Gastrointestinal hemorrhage.
To post Partum hemorrhages or those actively hemorrhaging a lot, not a little, but a lot during miscarriage as well.
2 liters of NS or LR after the loss of the equivalent of 2 units of prbc, is like adding more water to a Kool-Aid drink. Doesn't make it taste better. Just diluted watered down Kool-Aid.